TKL_ACVR2A (Activin receptor type-2A)

Total number of chains: 8
Active chains: 5
Family: TKL
Uniprot: AVR2A_HUMAN
Kinase Domain Residues: 192 - 481
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P27037-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P27037-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 184 - 489 0 None None Activin receptor type-2A
AF-P27037-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 184 - 489 0 None None Activin receptor type-2A
3Q4TB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 191 - 485 0 None None Activin receptor type-2A
3SOCB 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GVD Type1 191 - 486 0 None None Activin receptor type-2A
4ASXA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6OJ Type1 191 - 486 0 None None Activin receptor type-2A
3Q4TA 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi TAK Type1 191 - 484 0 None None Activin receptor type-2A
3SOCA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi GVD Type1 191 - 486 0 None None Activin receptor type-2A
4ASXB 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 6OJ Type1 191 - 486 0 None None Activin receptor type-2A

TKL_ACVR2A (Activin receptor type-2A)

Total number of chains: 8
Active chains: 5
Family: TKL
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 8 100.0% AF-P27037-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AVR2A_HUMAN AF-P27037-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 184 - 489 0 None None Activin receptor type-2A Homo sapiens
AVR2A_HUMAN AF-P27037-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 184 - 489 0 None None Activin receptor type-2A Homo sapiens
AVR2A_HUMAN 3Q4TB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 191 - 485 0 None None Activin receptor type-2A Homo sapiens
AVR2A_HUMAN 3SOCB 1.95 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii GVD Type1 191 - 486 0 None None Activin receptor type-2A Homo sapiens
AVR2A_HUMAN 4ASXA 2.05 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6OJ Type1 191 - 486 0 None None Activin receptor type-2A Homo sapiens
AVR2A_HUMAN 3Q4TA 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi TAK Type1 191 - 484 0 None None Activin receptor type-2A Homo sapiens
AVR2A_HUMAN 3SOCA 1.95 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi GVD Type1 191 - 486 0 None None Activin receptor type-2A Homo sapiens
AVR2A_HUMAN 4ASXB 2.05 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi 6OJ Type1 191 - 486 0 None None Activin receptor type-2A Homo sapiens

TKL_ACVR2A (Activin receptor type-2A)

Total number of chains: 0
Active chains: 0
Family: TKL
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Hover over column headers for tooltip help

UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism