Protein kinases in complex with ZVD

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLAminus 4 8SCEB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 8SCEA 1.89 Inactive DFGin BLAminus in-out in-in ZVD Type1
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 8SCEB 1.89 Active DFGin BLAminus in-in in-in ZVD Type1
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 8SCED 1.89 Active DFGin BLAminus in-in in-in ZVD Type1
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 8SCEE 1.89 Active DFGin BLAminus in-in in-in ZVD Type1

Protein kinases in complex with ZVD

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLAminus 4 8SCEB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 8SCEA 1.89 Inactive DFGin BLAminus in-out in-in ZVD Type1
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 8SCEB 1.89 Active DFGin BLAminus in-in in-in ZVD Type1
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 8SCED 1.89 Active DFGin BLAminus in-in in-in ZVD Type1
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 8SCEE 1.89 Active DFGin BLAminus in-in in-in ZVD Type1

Protein kinases in complex with ZVD

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type