LRRK1 (Leucine-rich repeat serine/threonine-protein kinase 1)

Group: TKL
Uniprot: LRRK1_HUMAN
Domain boundary: 1238 - 1522


Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q38SD2-K1A
DFGout None 5 8E06A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q38SD2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 1230 - 1530 None None 0
8E04A 3.8 Inactive DFGout None in-in none-none No_ligand No_ligand 381 - 2007 None None 23
8E05A 4.6 Inactive DFGout None in-in none-none No_ligand No_ligand 51 - 2007 None None 22
8E05B 4.6 Inactive DFGout None in-in none-none No_ligand No_ligand 51 - 2007 None None 22
8E06A 4.3 Inactive DFGout None in-out none-none No_ligand No_ligand 51 - 2007 None None 22
8FACA 3.92 Inactive DFGout None in-out out-none No_ligand No_ligand 341 - 2013 None None 19

LRRK1 (Leucine-rich repeat serine/threonine-protein kinase 1)

Group: TKL
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q38SD2-K1A
DFGout None 5 8E06A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens LRRK1_HUMAN AF-Q38SD2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 1230 - 1530 None None 0
Homo sapiens LRRK1_HUMAN 8E04A 3.8 Inactive DFGout None in-in none-none No_ligand No_ligand 381 - 2007 None None 23
Homo sapiens LRRK1_HUMAN 8E05A 4.6 Inactive DFGout None in-in none-none No_ligand No_ligand 51 - 2007 None None 22
Homo sapiens LRRK1_HUMAN 8E05B 4.6 Inactive DFGout None in-in none-none No_ligand No_ligand 51 - 2007 None None 22
Homo sapiens LRRK1_HUMAN 8E06A 4.3 Inactive DFGout None in-out none-none No_ligand No_ligand 51 - 2007 None None 22
Homo sapiens LRRK1_HUMAN 8FACA 3.92 Inactive DFGout None in-out out-none No_ligand No_ligand 341 - 2013 None None 19

LRRK1 (Leucine-rich repeat serine/threonine-protein kinase 1)

No non-human structures known.