| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | ACVR1 | ACVR1_HUMAN | 6SZMA | 1.42 | Inactive | DFGin‑BLAminus | in-out | in-out | nonTYR | APEdihe_aaiii | APEdist_iooi | M2Z, M2Z, M2Z | Allosteric, Allosteric, Type1 | 202 - 499 | 0 | None | None | Activin receptor type-1 |
| TKL | ACVR1 | ACVR1_HUMAN | 6SZMB | 1.42 | Inactive | DFGin‑BLAminus | in-out | in-out | nonTYR | APEdihe_aaiii | APEdist_iooi | M2Z | Type1 | 205 - 499 | 0 | None | None | Activin receptor type-1 |
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TKL | ACVR1 | ACVR1_HUMAN | 6SZMA | 1.42 | Inactive | DFGin‑BLAminus | in-out | in-out | nonTYR | APEdihe_aaiii | APEdist_iooi | M2Z, M2Z, M2Z | Allosteric, Allosteric, Type1 | 202 - 499 | 0 | None | None | Activin receptor type-1 | Homo sapiens |
| TKL | ACVR1 | ACVR1_HUMAN | 6SZMB | 1.42 | Inactive | DFGin‑BLAminus | in-out | in-out | nonTYR | APEdihe_aaiii | APEdist_iooi | M2Z | Type1 | 205 - 499 | 0 | None | None | Activin receptor type-1 | Homo sapiens |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | APEtype | APEdihe | APEdist | Ligand | Ligand Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|