9MZX

RIPK1 (Receptor-interacting serine/threonine-protein kinase 1)
Group: TKL
Uniprot: RIPK1_HUMAN
Organism: Homo sapiens
Domain boundary: 17 - 287
Resolu: 2.53

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus out-out out-out A1BU4 Type3 6 - 294 17
B Inactive DFGout BBAminus out-out out-out A1BU4 Type3 6 - 294 11
Representative sequence - Chain B
15 25 35 45
SLNVIKMKSS DFLEsaelds ggfgKVSLAF HRTQGLMIMK
55 65 75 85
TVYKGPNCIE HNEALLEEAK MMNRLRHSRV VKLLGVIIEE
95 105 115 125
GKYSLVMEYM EKGNLMHVLK AEMSTPLSVK GRIILEIIEG
135 145 155 165
MAYLHGKGVI HKDLKPENIL VDNDFHIKIA DLGLASFKMW
175 185 195 205
SKLNNEEHNE Lrevdgtakk ngGTLYYMAP EHLNDVNAKP
215 225 235 245
TEKSDVYSFA VVLWAIFANK EPYENAIAEQ QLIMAIKSGN
255 265 275 285
RPDVDDITEY CPREIISLMK LCWEANPEAR PTFPGIEEKF

RPFYLSQLE
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None