| Chain id | Group | Gene | UniprotID | Protein | Organism | Activity | Spatial | Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| B | STE | MAP2K1 | MP2K1_HUMAN | Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens | Inactive | DFGin | BLBplus | out-out | out-out | A1AHE | Type3 | 52 - 380 | 0 |
| D | STE | MAP2K1 | MP2K1_HUMAN | Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens | Inactive | DFGin | BLBplus | out-out | out-out | A1AHE | Type3 | 59 - 383 | 0 |
| A | TKL | RAF1 | RAF1_HUMAN | RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens | Inactive | DFGin | BLAminus | in-out | in-out | No_ligand | No_ligand | 342 - 625 | 5 |
| C | TKL | RAF1 | RAF1_HUMAN | RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens | Inactive | DFGin | BLAminus | in-out | in-out | No_ligand | No_ligand | 341 - 625 | 0 |
Representative sequence - Chain C
10 20 30 40
mspilgywki kglvqptrll leyleekyee hlyerdegdk
50 60 70 80
wrnkkfelgl efpnlpyyid gdvkltqsma iiryiadkhn
90 100 110 120
mlggcpkera eismlegavl dirygvsria yskdfetlkv
130 140 150 160
dflsklpeml kmfedrlchk tylngdhvth pdfmlydald
170 180 190 200
vvlymdpmcl dafpklvcfk krieaipqid kylksskyia
210 - 315 325
wplqgwqatf gggdhppksd sqpktpvpaq rerapvsgtq
335 345 355 365
eknkirprgq rdssdDWEIE ASEVMLSTRi gsgsFGTVYK
375 385 395 405
GKWHGDVAVK IlkvvdPTPE QFQAFRNEVA VLRKTRHVNI
415 425 435 445
LLFMGYMTKD NLAIVTQWCE GSSLYKHLHV QETKFQMFQL
455 465 475 485
IDIARQTAQG MDYLHAKNII HRDMKSNNIF LHEGLTVKIG
495 505 515 525
DFGLATVKSR WSGSQQVEQP TGSVLWMAPE VIRMQDNNPF
535 545 555 565
SFQSDVYSYG IVLYELMTGE LPYSHINNRD QIIFMVGRGY
575 585 595 605
ASPDLSKLYK NCPKAMKRLV ADCVKKVKEE RPLFPQILSS
615 625 635 645
IELLQHSLPK INRSASEPSL hraahtedin actlttsprl
pvf