Protein kinases in complex with K81 (Naporafenib)

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGout BBAminus 4 6N0PA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 8F7PA 2.74 Inactive DFGout BBAminus in-in out-out K81 Type2
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 8F7PB 2.74 Inactive DFGout BBAminus in-in out-out K81 Type2
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6N0PA 2.37 Inactive DFGout BBAminus in-in out-out K81 Type2
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6N0PB 2.37 Inactive DFGout BBAminus in-in none-out K81 Type2

Protein kinases in complex with K81

Total number of genes: 1
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGout BBAminus 4 6N0PA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 8F7PA 2.74 Inactive DFGout BBAminus in-in out-out K81 Type2
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 8F7PB 2.74 Inactive DFGout BBAminus in-in out-out K81 Type2
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6N0PA 2.37 Inactive DFGout BBAminus in-in out-out K81 Type2
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6N0PB 2.37 Inactive DFGout BBAminus in-in none-out K81 Type2

Protein kinases in complex with K81

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type