Ligand: 6HF

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 6YG3A
DFGout None 1 50.0% 5J9LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE MAP2K7 MP2K7_HUMAN 6YG3A 2.05 None DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn 6HF Type1 103 - 400 0 None None Dual specificity mitogen-activated protein kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5J9LA 2.752 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6HF Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7

Ligand: 6HF

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 6YG3A
DFGout None 1 50.0% 5J9LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE MAP2K7 MP2K7_HUMAN 6YG3A 2.05 None DFGin‑BLAminus in-na in-none nonTYR APEdihe_aannn APEdist_nnnn 6HF Type1 103 - 400 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5J9LA 2.752 Inactive DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6HF Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens

Ligand: 6HF

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism