9D8Z

ACVR1 (Activin receptor type-1)
Group: TKL
Uniprot: ACVR1_HUMAN
Organism: Homo sapiens
Domain boundary: 208 - 497
Resolu: 1.85

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in A1A3D Type1 203 - 499 0
B Inactive DFGin BLAminus in-out in-in A1A3D Type1 193 - 499 0
Representative sequence - Chain B
187 197 207 217
stladlldhs ctsgsGSGLP FLVQRTVARQ ITLLECVGKG
227 237 247 257
RYGEVWRGSW QGENVAVKIF SSRDEKSWFR ETELYNTVML
267 277 287 297
RHENILGFIA SDMTSRHSST QLWLITHYHE MGSLYDYLQL
307 317 327 337
TTLDTVSCLR IVLSIASGLA HLHIEIFGTQ GKPAIAHRDL
347 357 367 377
KSKNILVKKN GQCCIADLGL AVMHSQSTNQ LDVGNNPRVG
387 397 407 417
TKRYMAPEVL DETIQVDCFD SYKRVDIWAF GLVLWEVARR
427 437 447 457
MVSNGIVEDY KPPFYDVVPN DPSFEDMRKV VCVDQQRPNI
467 477 487 497
PNRWFSDPTL TSLAKLMKEC WYQNPSARLT ALRIKKTLTK
507
IDnsldklkt dc
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None