PDB: 4U97 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4U97A
DFGin None 1 50.0% 4U97B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL IRAK4 IRAK4_HUMAN 4U97A 2.65 None DFGin‑BLAminus in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 4U97B 2.65 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4

PDB: 4U97 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4U97A
DFGin None 1 50.0% 4U97B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL IRAK4 IRAK4_HUMAN 4U97A 2.65 None DFGin‑BLAminus in-in none-in nonTYR APEdihe_aaiii APEdist_iiii STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4 Homo sapiens
TKL IRAK4 IRAK4_HUMAN 4U97B 2.65 Inactive DFGin‑None in-in none-out nonTYR APEdihe_aaiii APEdist_nnno STU Type1 166 - 458 0 None D311N Interleukin-1 receptor-associated kinase 4 Homo sapiens

PDB: 4U97 — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism