Protein kinases in complex with P06 (Dabrafenib)

Total number of genes: 1
Total number of chains: 10
Spatial Dihedral Chains Representative
DFGin BLBminus 8 5HIEB
DFGin None 2 6V2UA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEA 3.0 Inactive DFGin BLBminus out-out out-out P06 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEB 3.0 Inactive DFGin BLBminus out-out out-out P06 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEC 3.0 Inactive DFGin BLBminus out-out none-out P06 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIED 3.0 Inactive DFGin BLBminus out-out none-out P06 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4XV2A 2.5 Inactive DFGin BLBminus out-out none-out P06 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4XV2B 2.5 Inactive DFGin BLBminus in-out none-out P06 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5CSWB 2.66 Inactive DFGin BLBminus out-out none-none P06 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6V2UB 3.78 Inactive DFGin BLBminus out-out none-none P06 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5CSWA 2.66 Inactive DFGin None out-out none-out P06 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6V2UA 3.78 Inactive DFGin None out-none none-out P06 Type1.5_Back

Protein kinases in complex with P06

Total number of genes: 1
Total number of chains: 10
Spatial Dihedral Chains Representative
DFGin BLBminus 8 5HIEB
DFGin None 2 6V2UA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEA 3.0 Inactive DFGin BLBminus out-out out-out P06 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEB 3.0 Inactive DFGin BLBminus out-out out-out P06 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEC 3.0 Inactive DFGin BLBminus out-out none-out P06 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIED 3.0 Inactive DFGin BLBminus out-out none-out P06 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4XV2A 2.5 Inactive DFGin BLBminus out-out none-out P06 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4XV2B 2.5 Inactive DFGin BLBminus in-out none-out P06 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5CSWB 2.66 Inactive DFGin BLBminus out-out none-none P06 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6V2UB 3.78 Inactive DFGin BLBminus out-out none-none P06 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5CSWA 2.66 Inactive DFGin None out-out none-out P06 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6V2UA 3.78 Inactive DFGin None out-none none-out P06 Type1.5_Back

Protein kinases in complex with P06

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type