8V2F

IRAK4 (Interleukin-1 receptor-associated kinase 4)
Group: TKL
Uniprot: IRAK4_HUMAN
Organism: Homo sapiens
Domain boundary: 175 - 456
Resolu: 2.09

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in YJU Type1 163 - 459 0
B Inactive DFGin BLAminus in-out in-in YJU Type1 162 - 459 0
C Inactive DFGin BLAminus in-out in-in YJU Type1 160 - 459 0
D Inactive DFGin BLAminus in-out in-in YJU Type1 163 - 459 3
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
         -          -        163        173 
msyyhhhhhh dydipttenl yfqsiavsdT RFHSFSFYEL 
       183        193        203        213 
KNVTNNFDER PISVGGNKMG EGGFGVVYKG YVNNTTVAVK 
       223        233        243        253 
KLAAMVDITT EELKQQFDQE IKVMAKCQHE NLVELLGFSS 
       263        273        283        293 
DGDDLCLVYV YMPNGSLLDR LSCLDGTPPL SWHMRCKIAQ 
       303        313        323        333 
GAANGINFLH ENHHIHRDIK SANILLDEAF TAKISDFGLA 
       343        353        363        373 
RASEKfaqTV MTSRIVGTTA YMAPEALRGE ITPKSDIYSF 
       383        393        403        413 
GVVLLEIITG LPAVDEHREP QLLLDIKEEI EDEEKTIEDY 
       423        433        443        453 
IDKKMNDADS TSVEAMYSVA SQCLHEKKNK RPDIKKVQQL 

LQEMTAs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X342,X345,X346