Ligand: 1FN

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 100.0% 3CE3A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR MET MET_HUMAN 3CE3A 2.4 Inactive DFGout‑BBAminus out-out none-out TYR APEdihe_oiiai APEdist_aaai 1FN Type2 1054 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor

Ligand: 1FN

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 66.7% 6OKOA
DFGout BBAminus 1 33.3% 3CE3A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR MET MET_HUMAN 3CE3A 2.4 Inactive DFGout‑BBAminus out-out none-out TYR APEdihe_oiiai APEdist_aaai 1FN Type2 1054 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor Homo sapiens
TKL RIPK3 RIPK3_MOUSE 6OKOA 2.1 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 1FN Type2 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 6OKOB 2.1 Inactive DFGout‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn 1FN Type2 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus

Ligand: 1FN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 2 100.0% 6OKOA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL RIPK3 RIPK3_MOUSE 6OKOA 2.1 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 1FN Type2 14 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus
TKL RIPK3 RIPK3_MOUSE 6OKOB 2.1 Inactive DFGout‑None in-out none-none nonTYR APEdihe_aannn APEdist_nnnn 1FN Type2 13 - 311 0 None None Receptor-interacting serine/threonine-protein kinase 3 Mus musculus