PDB: 3FAA — TKL TGFR1_HUMAN

Total number of chains: 5
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 3FAAC

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL TGFBR1 TGFR1_HUMAN 3FAAA 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3FAAB 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 501 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3FAAC 3.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3FAAD 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 3FAAE 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1

PDB: 3FAA — TKL TGFR1_HUMAN

Total number of chains: 5
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 3FAAC

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL TGFBR1 TGFR1_HUMAN 3FAAA 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3FAAB 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 501 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3FAAC 3.35 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3FAAD 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens
TKL TGFBR1 TGFR1_HUMAN 3FAAE 3.35 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii 55F Type1 171 - 500 0 None None TGF-beta receptor type-1 Homo sapiens

PDB: 3FAA — TKL TGFR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism