Ligand: TAK

Total number of chains: 9
Active chains: 1
Total number of genes: 5
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 66.7% 3Q4TA
DFGin None 2 22.2% 7JHGA
None None 1 11.1% 3AQVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK MELK MELK_HUMAN 6GVXA 2.24 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii TAK Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase
CAMK MELK MELK_HUMAN 6GVXB 2.24 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnni TAK Type1 1 - 335 0 None None Maternal embryonic leucine zipper kinase
CAMK PRKAA1 AAPK1_HUMAN 7JHGA 3.47 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo TAK Type1 22 - 559 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-1
CAMK PRKAA1 AAPK1_HUMAN 7M74A 3.93 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo TAK Type1 22 - 559 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-1
CAMK PRKAA2 AAPK2_HUMAN 3AQVA 2.08 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn TAK Type1 7 - 279 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2
TKL ACVR1 ACVR1_HUMAN 3H9RA 2.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi TAK Type1 172 - 499 0 None None Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 4C02A 2.17 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 178 - 499 0 None None Activin receptor type-1
TKL ACVR2A AVR2A_HUMAN 3Q4TA 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi TAK Type1 191 - 484 0 None None Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN 3Q4TB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 191 - 485 0 None None Activin receptor type-2A

Ligand: TAK

Total number of chains: 9
Active chains: 1
Total number of genes: 5
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 66.7% 3Q4TA
DFGin None 2 22.2% 7JHGA
None None 1 11.1% 3AQVA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK MELK MELK_HUMAN 6GVXA 2.24 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaiii APEdist_nnii TAK Type1 1 - 333 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK MELK MELK_HUMAN 6GVXB 2.24 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_nnni TAK Type1 1 - 335 0 None None Maternal embryonic leucine zipper kinase Homo sapiens
CAMK PRKAA1 AAPK1_HUMAN 7JHGA 3.47 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo TAK Type1 22 - 559 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Homo sapiens
CAMK PRKAA1 AAPK1_HUMAN 7M74A 3.93 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaioi APEdist_iooo TAK Type1 22 - 559 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-1 Homo sapiens
CAMK PRKAA2 AAPK2_HUMAN 3AQVA 2.08 Inactive None‑None out-out out-none nonTYR APEdihe_aannn APEdist_nnnn TAK Type1 7 - 279 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 3H9RA 2.35 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi TAK Type1 172 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 4C02A 2.17 Inactive DFGin‑BLAminus in-out in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 178 - 499 0 None None Activin receptor type-1 Homo sapiens
TKL ACVR2A AVR2A_HUMAN 3Q4TA 1.96 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_iooi TAK Type1 191 - 484 0 None None Activin receptor type-2A Homo sapiens
TKL ACVR2A AVR2A_HUMAN 3Q4TB 1.96 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii TAK Type1 191 - 485 0 None None Activin receptor type-2A Homo sapiens

Ligand: TAK

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism