PDB: AF-Q12852 — TKL M3K12_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q12852-K1A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K1A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 117 - 374 0 None None Mitogen-activated protein kinase kinase kinase 12
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K3A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 117 - 374 0 None None Mitogen-activated protein kinase kinase kinase 12

PDB: AF-Q12852 — TKL M3K12_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q12852-K1A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K1A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 117 - 374 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens
TKL MAP3K12 M3K12_HUMAN AF-Q12852-K3A -1.0 Active DFGin‑BLAminus in-na in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 117 - 374 0 None None Mitogen-activated protein kinase kinase kinase 12 Homo sapiens

PDB: AF-Q12852 — TKL M3K12_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism