Ligand: C6F (Gilteritinib)

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 50.0% 7AB1A
DFGout None 1 50.0% 6JQRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR FLT3 FLT3_HUMAN 6JQRA 2.2 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai C6F Type1 571 - 951 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR MERTK MERTK_HUMAN 7AB1A 1.93 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan C6F Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer

Ligand: C6F (Gilteritinib)

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 50.0% 7AB1A
DFGout None 1 50.0% 6JQRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR FLT3 FLT3_HUMAN 6JQRA 2.2 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai C6F Type1 571 - 951 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
TYR MERTK MERTK_HUMAN 7AB1A 1.93 Inactive DFGin‑None out-out none-none TYR APEdihe_nnnai APEdist_aaan C6F Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens

Ligand: C6F (Gilteritinib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism