Ligand

Protein kinases in complex with K3R

Total number of genes: 1

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGout	BBAminus	2	8S1BB
DFGout	None	1	8S1BA

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
TYR	KIT	KIT_HUMAN	Mast/stem cell growth factor receptor Kit	7ZW8A	2.119	Inactive	DFGout	BBAminus	in-out	out-in	K3R	Type1
TYR	KIT	KIT_HUMAN	Mast/stem cell growth factor receptor Kit	8S1BB	2.0	Inactive	DFGout	BBAminus	in-out	out-in	K3R K3R K3R	Type2 Allosteric Allosteric
TYR	KIT	KIT_HUMAN	Mast/stem cell growth factor receptor Kit	8S1BA	2.0	Inactive	DFGout	None	in-in	none-in	K3R	Type2

Protein kinases in complex with K3R

Total number of genes: 1

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGout	BBAminus	2	8S1BB
DFGout	None	1	8S1BA

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	TYR	KIT	KIT_HUMAN	Mast/stem cell growth factor receptor Kit	7ZW8A	2.119	Inactive	DFGout	BBAminus	in-out	out-in	K3R	Type1
Homo sapiens	TYR	KIT	KIT_HUMAN	Mast/stem cell growth factor receptor Kit	8S1BB	2.0	Inactive	DFGout	BBAminus	in-out	out-in	K3R K3R K3R	Type2 Allosteric Allosteric
Homo sapiens	TYR	KIT	KIT_HUMAN	Mast/stem cell growth factor receptor Kit	8S1BA	2.0	Inactive	DFGout	None	in-in	none-in	K3R	Type2

Protein kinases in complex with K3R

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type