Ligand: K3R

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 66.7% 8S1BB
DFGout None 1 33.3% 8S1BA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR KIT KIT_HUMAN 7ZW8A 2.119 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai K3R Type1 554 - 932 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S1BB 2.0 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai K3R, K3R, K3R Type2, Allosteric, Allosteric 565 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S1BA 2.0 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai K3R Type2 565 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit

Ligand: K3R

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 66.7% 8S1BB
DFGout None 1 33.3% 8S1BA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR KIT KIT_HUMAN 7ZW8A 2.119 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai K3R Type1 554 - 932 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S1BB 2.0 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai K3R, K3R, K3R Type2, Allosteric, Allosteric 565 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S1BA 2.0 Inactive DFGout‑None in-in none-in TYR APEdihe_iiiai APEdist_aaai K3R Type2 565 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens

Ligand: K3R

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism