Ligand: 95U

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5Z1DA
DFGout None 1 50.0% 5Z1EA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE MAP2K7 MP2K7_HUMAN 5Z1DA 2.28 None DFGin‑BLAminus in-na none-none nonTYR APEdihe_aaiai APEdist_nnni 95U Type1 103 - 403 0 None None Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 5Z1EA 2.3 Inactive DFGout‑None in-na out-none nonTYR APEdihe_aaiai APEdist_nnni 95U Type1 103 - 419 0 None None Dual specificity mitogen-activated protein kinase kinase 7

Ligand: 95U

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 5Z1DA
DFGout None 1 50.0% 5Z1EA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE MAP2K7 MP2K7_HUMAN 5Z1DA 2.28 None DFGin‑BLAminus in-na none-none nonTYR APEdihe_aaiai APEdist_nnni 95U Type1 103 - 403 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 5Z1EA 2.3 Inactive DFGout‑None in-na out-none nonTYR APEdihe_aaiai APEdist_nnni 95U Type1 103 - 419 0 None None Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens

Ligand: 95U

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism