TYR_NTRK2 (BDNF/NT-3 growth factors receptor)

Total number of chains: 6
Active chains: 2
Family: TYR
Uniprot: NTRK2_HUMAN
Kinase Domain Residues: 538 - 809
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 33.3% AF-Q16620-K1A
DFGout None 2 33.3% 4AT5A
DFGin None 1 16.7% 4AT3A
DFGout BBAminus 1 16.7% 4AT4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q16620-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 530 - 817 0 None None BDNF/NT-3 growth factors receptor
AF-Q16620-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 530 - 817 0 None None BDNF/NT-3 growth factors receptor
4AT3A 1.77 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa LTI Type1 527 - 822 0 None None BDNF/NT-3 growth factors receptor
4AT4A 2.36 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa T6E Type2 527 - 822 0 None None BDNF/NT-3 growth factors receptor
4ASZA 1.7 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 527 - 822 0 None None BDNF/NT-3 growth factors receptor
4AT5A 1.71 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa MUJ Type2 527 - 822 0 None None BDNF/NT-3 growth factors receptor

TYR_NTRK2 (BDNF/NT-3 growth factors receptor)

Total number of chains: 6
Active chains: 2
Family: TYR
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 33.3% AF-Q16620-K1A
DFGout None 2 33.3% 4AT5A
DFGin None 1 16.7% 4AT3A
DFGout BBAminus 1 16.7% 4AT4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
NTRK2_HUMAN AF-Q16620-K1A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 530 - 817 0 None None BDNF/NT-3 growth factors receptor Homo sapiens
NTRK2_HUMAN AF-Q16620-K3A -1.0 Active DFGin‑BLAminus DFGAsp-rot-in in-in in-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 530 - 817 0 None None BDNF/NT-3 growth factors receptor Homo sapiens
NTRK2_HUMAN 4AT3A 1.77 Inactive DFGin‑None DFGAsp-rot-in out-out out-in TYR APEdihe_iiiai APEdist_aaaa LTI Type1 527 - 822 0 None None BDNF/NT-3 growth factors receptor Homo sapiens
NTRK2_HUMAN 4AT4A 2.36 Inactive DFGout‑BBAminus DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa T6E Type2 527 - 822 0 None None BDNF/NT-3 growth factors receptor Homo sapiens
NTRK2_HUMAN 4ASZA 1.7 Inactive DFGout‑None DFGAsp-rot-out in-out out-in TYR APEdihe_iiiai APEdist_aaaa No_ligand No_ligand 527 - 822 0 None None BDNF/NT-3 growth factors receptor Homo sapiens
NTRK2_HUMAN 4AT5A 1.71 Inactive DFGout‑None DFGAsp-rot-in in-out out-in TYR APEdihe_iiiai APEdist_aaaa MUJ Type2 527 - 822 0 None None BDNF/NT-3 growth factors receptor Homo sapiens

TYR_NTRK2 (BDNF/NT-3 growth factors receptor)

Total number of chains: 0
Active chains: 0
Family: TYR
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

UniprotID PDB Resolution Activity_label Spatial_Dihedral_label DFG-Asp_rotamer_label ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism