TYR_PDGFRA (Platelet-derived growth factor receptor alpha)

Total number of chains: 15
Active chains: 4
Uniprot: PGFRA_HUMAN
Kinase Domain Residues: 593 - 952
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 5 33.3% 5K5XA
DFGin BLAminus 4 26.7% AF-P16234-K1A
DFGout BBAminus 3 20.0% 5GRNA
DFGin BLAplus 1 6.7% 6JOIA
DFGin BLBminus 1 6.7% 8XRRA
None None 1 6.7% 6JOJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-P16234-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 585 - 960 0 None None Platelet-derived growth factor receptor alpha
AF-P16234-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 585 - 960 0 None None Platelet-derived growth factor receptor alpha
8PQHA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9JI Type1 555 - 971 0 None T674I Platelet-derived growth factor receptor alpha
8PQIA 2.6 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9OO Type1 567 - 969 0 None T674I Platelet-derived growth factor receptor alpha
6JOIA 3.1 Inactive DFGin‑BLAplus in-out none-in TYR APEdihe_iiiai APEdist_aaai 6T2 Type1 569 - 973 0 None T674I Platelet-derived growth factor receptor alpha
8XRRA 2.57 Inactive DFGin‑BLBminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1LV8 Type1 338 - 730 0 None None receptor protein-tyrosine kinase
9GZHA 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1IRC Type2 583 - 958 0 None T674I Platelet-derived growth factor receptor alpha
5GRNA 1.77 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 748 Type2 583 - 958 0 None None Platelet-derived growth factor receptor alpha
6JOLA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 583 - 957 0 None None Platelet-derived growth factor receptor alpha
8PQKA 2.0 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 554 - 973 0 None T674I Platelet-derived growth factor receptor alpha
6A32A 1.87 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 554 - 973 0 None T674I Platelet-derived growth factor receptor alpha
8PQJA 1.82 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 553 - 973 0 None None Platelet-derived growth factor receptor alpha
5K5XA 2.168 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 554 - 973 0 None None Platelet-derived growth factor receptor alpha
6JOKA 3.8 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 556 - 973 0 None None Platelet-derived growth factor receptor alpha
6JOJA 2.6 Inactive None‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6T2 Type1 554 - 973 0 None None Platelet-derived growth factor receptor alpha

TYR_PDGFRA (Platelet-derived growth factor receptor alpha)

Total number of chains: 15
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGout None 5 33.3% 5K5XA
DFGin BLAminus 4 26.7% AF-P16234-K1A
DFGout BBAminus 3 20.0% 5GRNA
DFGin BLAplus 1 6.7% 6JOIA
DFGin BLBminus 1 6.7% 8XRRA
None None 1 6.7% 6JOJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
PGFRA_HUMAN AF-P16234-K1A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 585 - 960 0 None None Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN AF-P16234-K3A -1.0 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 585 - 960 0 None None Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 8PQHA 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9JI Type1 555 - 971 0 None T674I Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 8PQIA 2.6 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 9OO Type1 567 - 969 0 None T674I Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 6JOIA 3.1 Inactive DFGin‑BLAplus in-out none-in TYR APEdihe_iiiai APEdist_aaai 6T2 Type1 569 - 973 0 None T674I Platelet-derived growth factor receptor alpha Homo sapiens
A0A0B4J203_HUMAN 8XRRA 2.57 Inactive DFGin‑BLBminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1LV8 Type1 338 - 730 0 None None receptor protein-tyrosine kinase Homo sapiens
PGFRA_HUMAN 9GZHA 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1IRC Type2 583 - 958 0 None T674I Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 5GRNA 1.77 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 748 Type2 583 - 958 0 None None Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 6JOLA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 583 - 957 0 None None Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 8PQKA 2.0 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 554 - 973 0 None T674I Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 6A32A 1.87 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 554 - 973 0 None T674I Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 8PQJA 1.82 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 553 - 973 0 None None Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 5K5XA 2.168 Inactive DFGout‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 554 - 973 0 None None Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 6JOKA 3.8 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 556 - 973 0 None None Platelet-derived growth factor receptor alpha Homo sapiens
PGFRA_HUMAN 6JOJA 2.6 Inactive None‑None in-in out-in TYR APEdihe_iiiai APEdist_aaai 6T2 Type1 554 - 973 0 None None Platelet-derived growth factor receptor alpha Homo sapiens

TYR_PDGFRA (Platelet-derived growth factor receptor alpha)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism