PDGFRA (Platelet-derived growth factor receptor alpha)

Group: TYR

Uniprot: PGFRA_HUMAN

Domain boundary: 593 - 952

Total number of chains: 14

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	AF-P16234-K1A
DFGin	BLAplus	1	6JOIA
DFGin	BLBminus	1	8XRRA
DFGout	BBAminus	3	5GRNA
DFGout	None	5	5K5XA
None	None	1	6JOJA

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-P16234-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	585 - 960	None	None	0
8PQHA	2.5	Active	DFGin	BLAminus	in-in	in-in	9JI	Type1	555 - 971	T674I	None	0
8PQIA	2.6	Active	DFGin	BLAminus	in-in	in-in	9OO	Type1	567 - 969	T674I	None	10
6JOIA	3.1	Inactive	DFGin	BLAplus	in-out	none-in	6T2	Type1	569 - 973	T674I	None	15
8XRRA	2.57	Inactive	DFGin	BLBminus	in-in	in-in	A1LV8	Type1	338 - 730	None	None	11
9GZHA	2.2	Inactive	DFGout	BBAminus	in-in	out-in	A1IRC	Type2	583 - 958	T674I	None	0
5GRNA	1.77	Inactive	DFGout	BBAminus	in-in	out-in	748	Type2	583 - 958	None	None	0
6JOLA	1.9	Inactive	DFGout	BBAminus	in-in	out-in	STI	Type2	583 - 957	None	None	0
8PQKA	2.0	Inactive	DFGout	None	in-in	out-in	No_ligand	No_ligand	554 - 973	T674I	None	0
6A32A	1.87	Inactive	DFGout	None	in-in	out-in	No_ligand	No_ligand	554 - 973	T674I	None	0
8PQJA	1.82	Inactive	DFGout	None	in-in	out-in	No_ligand	No_ligand	553 - 973	None	None	0
5K5XA	2.168	Inactive	DFGout	None	in-in	out-in	No_ligand	No_ligand	554 - 973	None	None	0
6JOKA	3.8	Inactive	DFGout	None	in-out	out-in	B49	Type1	556 - 973	None	None	0
6JOJA	2.6	Inactive	None	None	in-in	out-in	6T2	Type1	554 - 973	None	None	0

PDGFRA (Platelet-derived growth factor receptor alpha)

Group: TYR

Total number of chains: 14

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	AF-P16234-K1A
DFGin	BLAplus	1	6JOIA
DFGin	BLBminus	1	8XRRA
DFGout	BBAminus	3	5GRNA
DFGout	None	5	5K5XA
None	None	1	6JOJA

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	PGFRA_HUMAN	AF-P16234-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	585 - 960	None	None	0
Homo sapiens	PGFRA_HUMAN	8PQHA	2.5	Active	DFGin	BLAminus	in-in	in-in	9JI	Type1	555 - 971	T674I	None	0
Homo sapiens	PGFRA_HUMAN	8PQIA	2.6	Active	DFGin	BLAminus	in-in	in-in	9OO	Type1	567 - 969	T674I	None	10
Homo sapiens	PGFRA_HUMAN	6JOIA	3.1	Inactive	DFGin	BLAplus	in-out	none-in	6T2	Type1	569 - 973	T674I	None	15
Homo sapiens	A0A0B4J203_HUMAN	8XRRA	2.57	Inactive	DFGin	BLBminus	in-in	in-in	A1LV8	Type1	338 - 730	None	None	11
Homo sapiens	PGFRA_HUMAN	9GZHA	2.2	Inactive	DFGout	BBAminus	in-in	out-in	A1IRC	Type2	583 - 958	T674I	None	0
Homo sapiens	PGFRA_HUMAN	5GRNA	1.77	Inactive	DFGout	BBAminus	in-in	out-in	748	Type2	583 - 958	None	None	0
Homo sapiens	PGFRA_HUMAN	6JOLA	1.9	Inactive	DFGout	BBAminus	in-in	out-in	STI	Type2	583 - 957	None	None	0
Homo sapiens	PGFRA_HUMAN	8PQKA	2.0	Inactive	DFGout	None	in-in	out-in	No_ligand	No_ligand	554 - 973	T674I	None	0
Homo sapiens	PGFRA_HUMAN	6A32A	1.87	Inactive	DFGout	None	in-in	out-in	No_ligand	No_ligand	554 - 973	T674I	None	0
Homo sapiens	PGFRA_HUMAN	8PQJA	1.82	Inactive	DFGout	None	in-in	out-in	No_ligand	No_ligand	553 - 973	None	None	0
Homo sapiens	PGFRA_HUMAN	5K5XA	2.168	Inactive	DFGout	None	in-in	out-in	No_ligand	No_ligand	554 - 973	None	None	0
Homo sapiens	PGFRA_HUMAN	6JOKA	3.8	Inactive	DFGout	None	in-out	out-in	B49	Type1	556 - 973	None	None	0
Homo sapiens	PGFRA_HUMAN	6JOJA	2.6	Inactive	None	None	in-in	out-in	6T2	Type1	554 - 973	None	None	0

PDGFRA (Platelet-derived growth factor receptor alpha)

No non-human structures known.