Ligand: WNT

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 1 50.0% 8YP4A
DFGout None 1 50.0% 8YP4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE MAP2K1 MP2K1_HUMAN 8YP4A 2.35 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoio APEdist_nnoo WNT Type1 34 - 384 0 None T286A,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1
STE MAP2K1 MP2K1_HUMAN 8YP4B 2.35 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aanoo APEdist_nnnn WNT Type1 43 - 383 0 None T286A,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1

Ligand: WNT

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 33.3% 8QR2A
DFGin None 1 33.3% 8YP4A
DFGout None 1 33.3% 8YP4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE MAP2K1 MP2K1_HUMAN 8YP4A 2.35 Inactive DFGin‑None out-out out-out nonTYR APEdihe_aaoio APEdist_nnoo WNT Type1 34 - 384 0 None T286A,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
STE MAP2K1 MP2K1_HUMAN 8YP4B 2.35 Inactive DFGout‑None out-out out-out nonTYR APEdihe_aanoo APEdist_nnnn WNT Type1 43 - 383 0 None T286A,T292A,S298A Dual specificity mitogen-activated protein kinase kinase 1 Homo sapiens
CMGC MAPK1 MK01_RAT 8QR2A 1.64 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii WNT Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus

Ligand: WNT

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 100.0% 8QR2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK1 MK01_RAT 8QR2A 1.64 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii WNT Type1 9 - 354 0 None None Mitogen-activated protein kinase 1 Rattus norvegicus