DDR1 (Epithelial discoidin domain-containing receptor 1)

Group: TYR
Uniprot: DDR1_HUMAN
Domain boundary: 610 - 907


Total number of chains: 42
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q08345-K1A
DFGinter None 5 6Y23A
DFGout BBAminus 33 6FIOA
DFGout None 3 5SB2A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q08345-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 602 - 913 None None 0
6Y23A 2.58 Inactive DFGinter None in-out out-in No_ligand No_ligand 574 - 907 Y569F,Y586F None 3
6Y23B 2.58 Inactive DFGinter None in-out out-in No_ligand No_ligand 574 - 910 Y569F,Y586F None 5
6Y23C 2.58 Inactive DFGinter None in-out out-in No_ligand No_ligand 574 - 911 Y569F,Y586F None 5
6BRJA 2.231 Inactive DFGinter None in-in out-in VX6 Type1 605 - 913 None None 0
6BSDA 2.606 Inactive DFGinter None in-in out-in 1N1 Type1 604 - 912 None None 2
5SAUA 1.8 Inactive DFGout BBAminus in-in out-in 1IF Type2 604 - 912 None None 0
5SAVA 1.76 Inactive DFGout BBAminus in-in out-in 1IJ Type2 602 - 909 None None 0
5SAWA 1.601 Inactive DFGout BBAminus in-in out-in 1IM Type2 603 - 907 None None 0
5SAXA 1.902 Inactive DFGout BBAminus in-in out-in 1IM Type2 601 - 913 None None 0
5SAYA 2.19 Inactive DFGout BBAminus in-in out-in 1IJ Type2 602 - 907 None None 0
5SAYB 2.19 Inactive DFGout BBAminus in-in out-in 1IJ Type2 602 - 911 None None 0
5SAZA 1.8 Inactive DFGout BBAminus in-in out-in 1IW Type2 603 - 913 None None 0
5SB0A 1.97 Inactive DFGout BBAminus in-in out-in 1IZ Type2 604 - 913 None None 0
5SB1A 1.53 Inactive DFGout BBAminus in-in out-in 1JI Type2 604 - 913 None None 0
6FEWA 1.44 Inactive DFGout BBAminus in-in out-in D6W Type2 603 - 911 None None 0
6FEXA 1.291 Inactive DFGout BBAminus in-in out-in D6Z Type2 602 - 908 None None 0
6FILA 1.73 Inactive DFGout BBAminus in-in out-in D6W Type2 604 - 912 None None 0
6FINA 1.67 Inactive DFGout BBAminus in-in out-in DJQ Type2 603 - 911 None None 0
6FIOA 1.99 Inactive DFGout BBAminus in-in out-in DJH Type2 598 - 912 None None 0
6FIQA 1.79 Inactive DFGout BBAminus in-in out-in DJW Type2 601 - 913 None None 0
3ZOSB 1.92 Inactive DFGout BBAminus in-in out-in 0LI Type2 601 - 913 None None 0
4BKJA 1.7 Inactive DFGout BBAminus in-in out-in STI Type2 601 - 913 None None 4
4BKJB 1.7 Inactive DFGout BBAminus in-in out-in STI Type2 601 - 913 None None 4
4CKRA 2.2 Inactive DFGout BBAminus in-in out-in DI1 Type2 601 - 913 None None 4
6GWRA 2.07 Inactive DFGout BBAminus in-in out-in FEW Type2 601 - 912 None None 0
6GWRB 2.07 Inactive DFGout BBAminus in-in out-in FEW Type2 602 - 908 None None 0
6HP9A 1.96 Inactive DFGout BBAminus in-in out-in GKB Type2 601 - 909 None None 0
6HP9B 1.96 Inactive DFGout BBAminus in-in out-in GKB Type2 603 - 909 None None 0
7BCMA 2.3 Inactive DFGout BBAminus in-in out-in TBK Type2 604 - 909 None None 0
7BCMB 2.3 Inactive DFGout BBAminus in-out out-in TBK Type2 604 - 911 None None 0
7BE6A 1.871 Inactive DFGout BBAminus in-in out-in TJW Type2 601 - 912 None None 0
5BVNA 2.21 Inactive DFGout BBAminus in-in out-in 4VD Type2 604 - 911 None None 0
5BVOA 1.98 Inactive DFGout BBAminus in-in out-in 4VE Type2 604 - 911 None None 0
5FDPA 2.25 Inactive DFGout BBAminus in-in out-in 5WR Type2 604 - 912 None None 0
5FDXA 2.65 Inactive DFGout BBAminus in-in out-in 5X1 Type2 604 - 909 None None 0
5FDXB 2.65 Inactive DFGout BBAminus in-in out-in 5X1 Type2 605 - 907 None None 0
3ZOSA 1.92 Inactive DFGout BBAminus in-in out-in 0LI 0LI Type2 Allosteric 602 - 913 None None 0
7FEHA 1.61 Inactive DFGout BBAminus in-in out-in 3UI Type3 603 - 912 None None 0
5BVWA 1.94 Inactive DFGout None in-in none-in 1N1 Type1 604 - 911 None None 4
5SB2A 1.6 Inactive DFGout None in-in out-in 1K2 Type2 603 - 912 None None 0
5BVKA 2.29 Inactive DFGout None in-in out-in 4VC Type3 604 - 911 None None 0

DDR1 (Epithelial discoidin domain-containing receptor 1)

Group: TYR
Total number of chains: 42
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q08345-K1A
DFGinter None 5 6Y23A
DFGout BBAminus 33 6FIOA
DFGout None 3 5SB2A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens DDR1_HUMAN AF-Q08345-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 602 - 913 None None 0
Homo sapiens DDR1_HUMAN 6Y23A 2.58 Inactive DFGinter None in-out out-in No_ligand No_ligand 574 - 907 Y569F,Y586F None 3
Homo sapiens DDR1_HUMAN 6Y23B 2.58 Inactive DFGinter None in-out out-in No_ligand No_ligand 574 - 910 Y569F,Y586F None 5
Homo sapiens DDR1_HUMAN 6Y23C 2.58 Inactive DFGinter None in-out out-in No_ligand No_ligand 574 - 911 Y569F,Y586F None 5
Homo sapiens DDR1_HUMAN 6BRJA 2.231 Inactive DFGinter None in-in out-in VX6 Type1 605 - 913 None None 0
Homo sapiens DDR1_HUMAN 6BSDA 2.606 Inactive DFGinter None in-in out-in 1N1 Type1 604 - 912 None None 2
Homo sapiens DDR1_HUMAN 5SAUA 1.8 Inactive DFGout BBAminus in-in out-in 1IF Type2 604 - 912 None None 0
Homo sapiens DDR1_HUMAN 5SAVA 1.76 Inactive DFGout BBAminus in-in out-in 1IJ Type2 602 - 909 None None 0
Homo sapiens DDR1_HUMAN 5SAWA 1.601 Inactive DFGout BBAminus in-in out-in 1IM Type2 603 - 907 None None 0
Homo sapiens DDR1_HUMAN 5SAXA 1.902 Inactive DFGout BBAminus in-in out-in 1IM Type2 601 - 913 None None 0
Homo sapiens DDR1_HUMAN 5SAYA 2.19 Inactive DFGout BBAminus in-in out-in 1IJ Type2 602 - 907 None None 0
Homo sapiens DDR1_HUMAN 5SAYB 2.19 Inactive DFGout BBAminus in-in out-in 1IJ Type2 602 - 911 None None 0
Homo sapiens DDR1_HUMAN 5SAZA 1.8 Inactive DFGout BBAminus in-in out-in 1IW Type2 603 - 913 None None 0
Homo sapiens DDR1_HUMAN 5SB0A 1.97 Inactive DFGout BBAminus in-in out-in 1IZ Type2 604 - 913 None None 0
Homo sapiens DDR1_HUMAN 5SB1A 1.53 Inactive DFGout BBAminus in-in out-in 1JI Type2 604 - 913 None None 0
Homo sapiens DDR1_HUMAN 6FEWA 1.44 Inactive DFGout BBAminus in-in out-in D6W Type2 603 - 911 None None 0
Homo sapiens DDR1_HUMAN 6FEXA 1.291 Inactive DFGout BBAminus in-in out-in D6Z Type2 602 - 908 None None 0
Homo sapiens DDR1_HUMAN 6FILA 1.73 Inactive DFGout BBAminus in-in out-in D6W Type2 604 - 912 None None 0
Homo sapiens DDR1_HUMAN 6FINA 1.67 Inactive DFGout BBAminus in-in out-in DJQ Type2 603 - 911 None None 0
Homo sapiens DDR1_HUMAN 6FIOA 1.99 Inactive DFGout BBAminus in-in out-in DJH Type2 598 - 912 None None 0
Homo sapiens DDR1_HUMAN 6FIQA 1.79 Inactive DFGout BBAminus in-in out-in DJW Type2 601 - 913 None None 0
Homo sapiens DDR1_HUMAN 3ZOSB 1.92 Inactive DFGout BBAminus in-in out-in 0LI Type2 601 - 913 None None 0
Homo sapiens DDR1_HUMAN 4BKJA 1.7 Inactive DFGout BBAminus in-in out-in STI Type2 601 - 913 None None 4
Homo sapiens DDR1_HUMAN 4BKJB 1.7 Inactive DFGout BBAminus in-in out-in STI Type2 601 - 913 None None 4
Homo sapiens DDR1_HUMAN 4CKRA 2.2 Inactive DFGout BBAminus in-in out-in DI1 Type2 601 - 913 None None 4
Homo sapiens DDR1_HUMAN 6GWRA 2.07 Inactive DFGout BBAminus in-in out-in FEW Type2 601 - 912 None None 0
Homo sapiens DDR1_HUMAN 6GWRB 2.07 Inactive DFGout BBAminus in-in out-in FEW Type2 602 - 908 None None 0
Homo sapiens DDR1_HUMAN 6HP9A 1.96 Inactive DFGout BBAminus in-in out-in GKB Type2 601 - 909 None None 0
Homo sapiens DDR1_HUMAN 6HP9B 1.96 Inactive DFGout BBAminus in-in out-in GKB Type2 603 - 909 None None 0
Homo sapiens DDR1_HUMAN 7BCMA 2.3 Inactive DFGout BBAminus in-in out-in TBK Type2 604 - 909 None None 0
Homo sapiens DDR1_HUMAN 7BCMB 2.3 Inactive DFGout BBAminus in-out out-in TBK Type2 604 - 911 None None 0
Homo sapiens DDR1_HUMAN 7BE6A 1.871 Inactive DFGout BBAminus in-in out-in TJW Type2 601 - 912 None None 0
Homo sapiens DDR1_HUMAN 5BVNA 2.21 Inactive DFGout BBAminus in-in out-in 4VD Type2 604 - 911 None None 0
Homo sapiens DDR1_HUMAN 5BVOA 1.98 Inactive DFGout BBAminus in-in out-in 4VE Type2 604 - 911 None None 0
Homo sapiens DDR1_HUMAN 5FDPA 2.25 Inactive DFGout BBAminus in-in out-in 5WR Type2 604 - 912 None None 0
Homo sapiens DDR1_HUMAN 5FDXA 2.65 Inactive DFGout BBAminus in-in out-in 5X1 Type2 604 - 909 None None 0
Homo sapiens DDR1_HUMAN 5FDXB 2.65 Inactive DFGout BBAminus in-in out-in 5X1 Type2 605 - 907 None None 0
Homo sapiens DDR1_HUMAN 3ZOSA 1.92 Inactive DFGout BBAminus in-in out-in 0LI 0LI Type2 Allosteric 602 - 913 None None 0
Homo sapiens DDR1_HUMAN 7FEHA 1.61 Inactive DFGout BBAminus in-in out-in 3UI Type3 603 - 912 None None 0
Homo sapiens DDR1_HUMAN 5BVWA 1.94 Inactive DFGout None in-in none-in 1N1 Type1 604 - 911 None None 4
Homo sapiens DDR1_HUMAN 5SB2A 1.6 Inactive DFGout None in-in out-in 1K2 Type2 603 - 912 None None 0
Homo sapiens DDR1_HUMAN 5BVKA 2.29 Inactive DFGout None in-in out-in 4VC Type3 604 - 911 None None 0

DDR1 (Epithelial discoidin domain-containing receptor 1)

No non-human structures known.