OTHER_MLKL (Mixed lineage kinase domain-like protein)

Total number of chains: 15
Active chains: 0
Family: OTHER
Uniprot: MLKL_HUMAN
Kinase Domain Residues: 201 - 468
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 8 53.3% 4MWIA
DFGin BLAplus 3 20.0% 7JXUA
None None 2 13.3% 5KNJB
DFGin BLAminus 1 6.7% 6O5ZA
DFGout None 1 6.7% 6O5ZB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
6O5ZA 2.285 Pseudo DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein
7JXUA 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein
7JXUB 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein
7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein
4MWIA 1.7 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo PXN Allosteric 193 - 470 0 None None Mixed lineage kinase domain-like protein
6BWKA 2.79 Pseudo DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 192 - 470 0 None T357E,S358E Mixed lineage kinase domain-like protein
7JW7A 2.63 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein
8SLZA 2.3 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 469 0 TPO357,SEP358 None Mixed lineage kinase domain-like protein
4M67A 1.9 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 469 0 None None Mixed lineage kinase domain-like protein
6LK6A 2.41 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357A,S358A Mixed lineage kinase domain-like protein
6LK5A 2.5 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357E,S358D Mixed lineage kinase domain-like protein
5KO1A 2.16 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo 6UY Type1 192 - 470 0 None E366A,K367A Mixed lineage kinase domain-like protein
6O5ZB 2.285 Pseudo DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno LN4 Type2 190 - 467 0 None None Mixed lineage kinase domain-like protein
5KNJA 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 193 - 468 0 None E366A,K367A Mixed lineage kinase domain-like protein
5KNJB 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 192 - 469 0 None E366A,K367A Mixed lineage kinase domain-like protein

OTHER_MLKL (Mixed lineage kinase domain-like protein)

Total number of chains: 23
Active chains: 0
Family: OTHER
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 13 56.5% 6VC0A
DFGin BLAplus 5 21.7% 7JXUA
None None 3 13.0% 4M69B
DFGin BLAminus 1 4.3% 6O5ZA
DFGout None 1 4.3% 6O5ZB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
F6S337_HORSE 6VC0A 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 536 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
F6S337_HORSE 6VC0B 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 258 - 537 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
F6S337_HORSE 6VC0C 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 541 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
MLKL_HUMAN 6O5ZA 2.285 Pseudo DFGin‑BLAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 7JXUA 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 7JXUB 2.44 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 471 0 None None Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 7MONA 2.23 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo ZL1 Type1 191 - 469 0 None None Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 4MWIA 1.7 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo PXN Allosteric 193 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 6BWKA 2.79 Pseudo DFGin‑BLBminus in-none none-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 192 - 470 0 None T357E,S358E Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 7JW7A 2.63 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno No_ligand No_ligand 191 - 470 0 None None Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 8SLZA 2.3 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 191 - 469 0 TPO357,SEP358 None Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 4M67A 1.9 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 469 0 None None Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 6LK6A 2.41 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357A,S358A Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 6LK5A 2.5 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 192 - 470 0 None T357E,S358D Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 5KO1A 2.16 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo 6UY Type1 192 - 470 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 6O5ZB 2.285 Pseudo DFGout‑None in-out none-out nonTYR APEdihe_aaoii APEdist_nnno LN4 Type2 190 - 467 0 None None Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 5KNJA 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 193 - 468 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
MLKL_HUMAN 5KNJB 2.88 Pseudo None‑None in-in none-out nonTYR APEdihe_aaoii APEdist_nnno 6UX Type1 192 - 469 0 None E366A,K367A Mixed lineage kinase domain-like protein Homo sapiens
MLKL_MOUSE 4M68A 1.696 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
MLKL_MOUSE 4BTFA 2.604 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 2 - 463 0 None None Mixed lineage kinase domain-like protein Mus musculus
MLKL_MOUSE 4M69B 2.497 Pseudo None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
D3ZKP6_RAT 6VBZA 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 183 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
D3ZKP6_RAT 6VBZB 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 182 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus

OTHER_MLKL (Mixed lineage kinase domain-like protein)

Total number of chains: 8
Active chains: 0
Family: OTHER
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 5 62.5% 6VC0A
DFGin BLAplus 2 25.0% 4BTFA
None None 1 12.5% 4M69B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
F6S337_HORSE 6VC0A 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 536 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
F6S337_HORSE 6VC0B 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_nooo No_ligand No_ligand 258 - 537 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
F6S337_HORSE 6VC0C 2.746 Pseudo DFGin‑BLBminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo No_ligand No_ligand 258 - 541 0 None None Mixed lineage kinase domain like pseudokinase Equus caballus
MLKL_MOUSE 4M68A 1.696 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
MLKL_MOUSE 4BTFA 2.604 Pseudo DFGin‑BLAplus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno No_ligand No_ligand 2 - 463 0 None None Mixed lineage kinase domain-like protein Mus musculus
MLKL_MOUSE 4M69B 2.497 Pseudo None‑None out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 182 - 466 0 None None Mixed lineage kinase domain-like protein Mus musculus
D3ZKP6_RAT 6VBZA 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 183 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus
D3ZKP6_RAT 6VBZB 2.192 Pseudo DFGin‑BLBminus in-in none-out nonTYR APEdihe_aaooi APEdist_nooo No_ligand No_ligand 182 - 454 0 None None Mixed lineage kinase domain-like protein Rattus norvegicus