Ligand: CCX

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 75.0% 3LW0A
DFGout None 1 25.0% 3LW0D

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR IGF1R IGF1R_HUMAN 3LW0A 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0B 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0C 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0D 1.79 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor

Ligand: CCX

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 75.0% 3LW0A
DFGout None 1 25.0% 3LW0D

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR IGF1R IGF1R_HUMAN 3LW0A 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LW0B 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LW0C 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LW0D 1.79 Inactive DFGout‑None in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor Homo sapiens

Ligand: CCX

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism