Ligand: EDD

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 3NNXA
DFGout None 1 50.0% 3NNWA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK14 MK14_HUMAN 3NNXA 2.28 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nioo EDD Type3 5 - 352 0 PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3NNWA 1.89 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaooi APEdist_oooo EDD Type2 4 - 352 0 None None Mitogen-activated protein kinase 14

Ligand: EDD

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 50.0% 3NNXA
DFGout None 1 50.0% 3NNWA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK14 MK14_HUMAN 3NNXA 2.28 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nioo EDD Type3 5 - 352 0 PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3NNWA 1.89 Inactive DFGout‑None in-in out-out nonTYR APEdihe_aaooi APEdist_oooo EDD Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens

Ligand: EDD

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism