Ligand: IED

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9FPDA
DFGout None 1 50.0% 8PYMAAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL MAP3K7 M3K7_HUMAN 9FPDA 2.402 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_iiii A1IED Type1 31 - 496 0 TPO187,SEP192 None Mitogen-activated protein kinase kinase kinase 7
TYR IGF1R IGF1R_HUMAN 8PYMAAA 2.652 Inactive DFGout‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai IED Type2 984 - 1270 0 None None Insulin-like growth factor 1 receptor

Ligand: IED

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 9FPDA
DFGout None 1 50.0% 8PYMAAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL MAP3K7 M3K7_HUMAN 9FPDA 2.402 None DFGin‑BLAminus in-in in-none nonTYR APEdihe_aaini APEdist_iiii A1IED Type1 31 - 496 0 TPO187,SEP192 None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TYR IGF1R IGF1R_HUMAN 8PYMAAA 2.652 Inactive DFGout‑None out-out out-in TYR APEdihe_iiiai APEdist_aaai IED Type2 984 - 1270 0 None None Insulin-like growth factor 1 receptor Homo sapiens

Ligand: IED

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism