Protein kinases in complex with NIL (Nilotinib)

Total number of genes: 3
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGout BBAminus 5 3CS9A
DFGout None 2 9CJ1A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC MAPK11 MK11_HUMAN Mitogen-activated protein kinase 11 3GP0A 1.9 Inactive DFGout BBAminus in-out none-out NIL Type2
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 9CJ1A 1.8 Inactive DFGout None in-in none-out NIL Type2
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3CS9A 2.21 Inactive DFGout BBAminus in-in out-in NIL Type2
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3CS9B 2.21 Inactive DFGout BBAminus in-in none-none NIL Type2
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3CS9C 2.21 Inactive DFGout BBAminus in-in none-none NIL Type2
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3CS9D 2.21 Inactive DFGout BBAminus in-in out-in NIL Type2
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 5MO4A 2.17 Inactive DFGout None in-in none-out NIL AY7 Type2 Allosteric

Protein kinases in complex with NIL

Total number of genes: 3
Total number of chains: 7
Spatial Dihedral Chains Representative
DFGout BBAminus 5 3CS9A
DFGout None 2 9CJ1A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC MAPK11 MK11_HUMAN Mitogen-activated protein kinase 11 3GP0A 1.9 Inactive DFGout BBAminus in-out none-out NIL Type2
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 9CJ1A 1.8 Inactive DFGout None in-in none-out NIL Type2
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3CS9A 2.21 Inactive DFGout BBAminus in-in out-in NIL Type2
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3CS9B 2.21 Inactive DFGout BBAminus in-in none-none NIL Type2
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3CS9C 2.21 Inactive DFGout BBAminus in-in none-none NIL Type2
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3CS9D 2.21 Inactive DFGout BBAminus in-in out-in NIL Type2
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 5MO4A 2.17 Inactive DFGout None in-in none-out NIL AY7 Type2 Allosteric

Protein kinases in complex with NIL

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type