Ligand: QCR

Total number of chains: 2
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 2 8D73A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 8D73A 2.17 Active DFGin‑BLAminus in-in in-in QCR Type1.5_Back 703 - 1011 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8D73B 2.17 Active DFGin‑BLAminus in-in in-in QCR Type1.5_Back 704 - 1012 0 None T790M,L858R,V948R Epidermal growth factor receptor

Ligand: QCR

Total number of chains: 2
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 2 8D73A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 8D73A 2.17 Active DFGin‑BLAminus in-in in-in QCR Type1.5_Back 703 - 1011 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 8D73B 2.17 Active DFGin‑BLAminus in-in in-in QCR Type1.5_Back 704 - 1012 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens

Ligand: QCR

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism