Ligand: 8AM

Total number of chains: 1
Spatial label Dihedral label Number of Chains Representative
DFGout BBAminus 1 5UG9A

Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 5UG9A 1.33 Inactive DFGout‑BBAminus out-out in-in 8AM Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor

Ligand: 8AM

Total number of chains: 1
Spatial label Dihedral label Number of Chains Representative
DFGout BBAminus 1 5UG9A

Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 5UG9A 1.33 Inactive DFGout‑BBAminus out-out in-in 8AM Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens

Ligand: 8AM

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative

Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism