PDB: 4WD5 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4WD5A
DFGinter None 1 50.0% 4WD5B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 4WD5A 3.3 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_iiiai APEdist_aaao 3LH Type1 694 - 1021 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4WD5B 3.3 Inactive DFGinter‑None in-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 697 - 1016 0 None T790M Epidermal growth factor receptor

PDB: 4WD5 — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4WD5A
DFGinter None 1 50.0% 4WD5B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 4WD5A 3.3 Inactive DFGin‑BLAminus out-out in-out TYR APEdihe_iiiai APEdist_aaao 3LH Type1 694 - 1021 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4WD5B 3.3 Inactive DFGinter‑None in-out out-out TYR APEdihe_iiiai APEdist_aaao No_ligand No_ligand 697 - 1016 0 None T790M Epidermal growth factor receptor Homo sapiens

PDB: 4WD5 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism