KinCore

Ligand: MWU

Total number of chains: 3

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	3	8HV3A

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein
TYR	EGFR	EGFR_HUMAN	8HV4A	2.2	Active	DFGin‑BLAminus	in-in	in-in	PE5, MWU	Allosteric, Type1	696 - 1020	3	None	E865A,E866A,K867A	Epidermal growth factor receptor
TYR	EGFR	EGFR_HUMAN	8HV3A	2.4	Active	DFGin‑BLAminus	in-in	in-in	PE5, MWU	Allosteric, Type1	696 - 1020	0	None	E865A,E866A,K867A	Epidermal growth factor receptor
TYR	EGFR	EGFR_HUMAN	8HV2A	2.8	Active	DFGin‑BLAminus	in-in	in-in	MWU	Type1	697 - 1019	5	None	None	Epidermal growth factor receptor

Ligand: MWU

Total number of chains: 3

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	3	8HV3A

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism
TYR	EGFR	EGFR_HUMAN	8HV4A	2.2	Active	DFGin‑BLAminus	in-in	in-in	PE5, MWU	Allosteric, Type1	696 - 1020	3	None	E865A,E866A,K867A	Epidermal growth factor receptor	Homo sapiens
TYR	EGFR	EGFR_HUMAN	8HV3A	2.4	Active	DFGin‑BLAminus	in-in	in-in	PE5, MWU	Allosteric, Type1	696 - 1020	0	None	E865A,E866A,K867A	Epidermal growth factor receptor	Homo sapiens
TYR	EGFR	EGFR_HUMAN	8HV2A	2.8	Active	DFGin‑BLAminus	in-in	in-in	MWU	Type1	697 - 1019	5	None	None	Epidermal growth factor receptor	Homo sapiens

Ligand: MWU

Total number of chains: 0

Spatial label	Dihedral label	Number of Chains	Representative

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism