Ligand: A1IMS

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 9DF3A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 9DF2A 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IMS Type1.5_Back 701 - 1004 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9DF3A 1.68 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IMS Type1.5_Back 701 - 1022 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL7A 1.878 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IMS Type1.5_Back 702 - 1019 0 None V948R Epidermal growth factor receptor

Ligand: A1IMS

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 9DF3A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 9DF2A 2.5 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IMS Type1.5_Back 701 - 1004 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9DF3A 1.68 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IMS Type1.5_Back 701 - 1022 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GL7A 1.878 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IMS Type1.5_Back 702 - 1019 0 None V948R Epidermal growth factor receptor Homo sapiens

Ligand: A1IMS

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism