PDB: 2JIV — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 50.0% 2JIVB
DFGin None 1 50.0% 2JIVA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 2JIVB 3.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_ooiai APEdist_aaao HKI Type1.5_Back 699 - 982 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JIVA 3.5 Inactive DFGin‑None out-out out-none TYR APEdihe_niiai APEdist_aaai HKI Type1.5_Back 700 - 984 0 None T790M Epidermal growth factor receptor

PDB: 2JIV — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 1 50.0% 2JIVB
DFGin None 1 50.0% 2JIVA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 2JIVB 3.5 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_ooiai APEdist_aaao HKI Type1.5_Back 699 - 982 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2JIVA 3.5 Inactive DFGin‑None out-out out-none TYR APEdihe_niiai APEdist_aaai HKI Type1.5_Back 700 - 984 0 None T790M Epidermal growth factor receptor Homo sapiens

PDB: 2JIV — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism