| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 5YU9A | 1.95 | Inactive | DFGin‑BLBtrans | out-out | out-out | 1E8 | Type1 | 700 - 1017 | 12 | None | T790M | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 5YU9B | 1.95 | Inactive | DFGin‑BLBtrans | out-out | out-out | 1E8 | Type1 | 699 - 1011 | 13 | None | T790M | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 5YU9C | 1.95 | Inactive | DFGin‑BLBtrans | out-out | out-out | 1E8 | Type1 | 697 - 1021 | 12 | None | T790M | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 5YU9D | 1.95 | Inactive | DFGin‑BLBtrans | out-out | out-out | 1E8 | Type1 | 700 - 1012 | 13 | None | T790M | Epidermal growth factor receptor |
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 5YU9A | 1.95 | Inactive | DFGin‑BLBtrans | out-out | out-out | 1E8 | Type1 | 700 - 1017 | 12 | None | T790M | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 5YU9B | 1.95 | Inactive | DFGin‑BLBtrans | out-out | out-out | 1E8 | Type1 | 699 - 1011 | 13 | None | T790M | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 5YU9C | 1.95 | Inactive | DFGin‑BLBtrans | out-out | out-out | 1E8 | Type1 | 697 - 1021 | 12 | None | T790M | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 5YU9D | 1.95 | Inactive | DFGin‑BLBtrans | out-out | out-out | 1E8 | Type1 | 700 - 1012 | 13 | None | T790M | Epidermal growth factor receptor | Homo sapiens |
| Spatial label | Dihedral label | Number of Chains | Representative |
|---|
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|