Ligand: ITQ

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 2ITQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 2ITWA 2.88 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ITQ Type1 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITQA 2.68 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ITQ Type1 697 - 1018 0 None G719S Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2ITUA 2.8 Inactive DFGin‑BLAminus in-out in-none TYR APEdihe_nniai APEdist_aaai ITQ Type1 696 - 1019 0 None L858R Epidermal growth factor receptor

Ligand: ITQ

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 2ITQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 2ITWA 2.88 Inactive DFGin‑BLAminus in-out in-in TYR APEdihe_iiiai APEdist_aaai ITQ Type1 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2ITQA 2.68 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai ITQ Type1 697 - 1018 0 None G719S Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 2ITUA 2.8 Inactive DFGin‑BLAminus in-out in-none TYR APEdihe_nniai APEdist_aaai ITQ Type1 696 - 1019 0 None L858R Epidermal growth factor receptor Homo sapiens

Ligand: ITQ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism