| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 7JXLB | 2.4 | Inactive | DFGin‑BLBplus | out-out | out-none | VO7 | Type1 | 700 - 1005 | 15 | None | T790M,V948R | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXLC | 2.4 | Inactive | DFGin‑BLBplus | out-out | out-out | VO7 | Type1 | 700 - 1007 | 14 | None | T790M,V948R | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXLD | 2.4 | Inactive | DFGin‑BLBplus | out-out | out-none | VO7 | Type1 | 700 - 1007 | 16 | None | T790M,V948R | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7JXLA | 2.4 | Inactive | DFGin‑BLBtrans | out-out | out-none | VO7 | Type1 | 701 - 1013 | 14 | None | T790M,V948R | Epidermal growth factor receptor |
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 7JXLB | 2.4 | Inactive | DFGin‑BLBplus | out-out | out-none | VO7 | Type1 | 700 - 1005 | 15 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 7JXLC | 2.4 | Inactive | DFGin‑BLBplus | out-out | out-out | VO7 | Type1 | 700 - 1007 | 14 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 7JXLD | 2.4 | Inactive | DFGin‑BLBplus | out-out | out-none | VO7 | Type1 | 700 - 1007 | 16 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 7JXLA | 2.4 | Inactive | DFGin‑BLBtrans | out-out | out-none | VO7 | Type1 | 701 - 1013 | 14 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| Spatial label | Dihedral label | Number of Chains | Representative |
|---|
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|