Ligand: ZRT (Lazertinib, Lazcluze)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 2 66.7% 7UKWB
DFGin BLAminus 1 33.3% 7UKVA
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 7UKVA 2.4 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ZRT Type1 696 - 1018 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7UKWB 2.6 Inactive DFGin‑BLBtrans out-out none-none TYR APEdihe_nniai APEdist_aaai ZRT Type1 702 - 1010 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7UKWC 2.6 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ZRT Type1 700 - 1005 0 None T790M,V948R Epidermal growth factor receptor

Ligand: ZRT (Lazertinib, Lazcluze)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 2 66.7% 7UKWB
DFGin BLAminus 1 33.3% 7UKVA
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 7UKVA 2.4 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai ZRT Type1 696 - 1018 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7UKWB 2.6 Inactive DFGin‑BLBtrans out-out none-none TYR APEdihe_nniai APEdist_aaai ZRT Type1 702 - 1010 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7UKWC 2.6 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai ZRT Type1 700 - 1005 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: ZRT (Lazertinib, Lazcluze)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism