PDB: 7U98 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 7U98B
DFGin None 1 25.0% 7U98A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 7U98B 3.42 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao M1O Type1 701 - 1005 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98C 3.42 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao M1O Type1 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98D 3.42 Inactive DFGin‑BLBtrans out-out none-out TYR APEdihe_nniai APEdist_aaao M1O Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7U98A 3.42 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan M1O Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor

PDB: 7U98 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 3 75.0% 7U98B
DFGin None 1 25.0% 7U98A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 7U98B 3.42 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_niiai APEdist_aaao M1O Type1 701 - 1005 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7U98C 3.42 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_nniai APEdist_aaao M1O Type1 702 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7U98D 3.42 Inactive DFGin‑BLBtrans out-out none-out TYR APEdihe_nniai APEdist_aaao M1O Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 7U98A 3.42 Inactive DFGin‑None out-out out-none TYR APEdihe_nnnai APEdist_aaan M1O Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 7U98 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism