KinCore

PDB: 8EME — TYR EGFR_HUMAN

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	1	8EMEB
DFGin	None	1	8EMEA

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein
TYR	EGFR	EGFR_HUMAN	8EMEB	3.32	Inactive	DFGin‑BLAminus	out-out	none-none	ZNL	Type1	702 - 1007	19	None	T790M,V948R	Epidermal growth factor receptor
TYR	EGFR	EGFR_HUMAN	8EMEA	3.32	Inactive	DFGin‑None	out-out	none-none	No_ligand	No_ligand	700 - 1007	21	None	T790M,V948R	Epidermal growth factor receptor

PDB: 8EME — TYR EGFR_HUMAN

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	1	8EMEB
DFGin	None	1	8EMEA

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism
TYR	EGFR	EGFR_HUMAN	8EMEB	3.32	Inactive	DFGin‑BLAminus	out-out	none-none	ZNL	Type1	702 - 1007	19	None	T790M,V948R	Epidermal growth factor receptor	Homo sapiens
TYR	EGFR	EGFR_HUMAN	8EMEA	3.32	Inactive	DFGin‑None	out-out	none-none	No_ligand	No_ligand	700 - 1007	21	None	T790M,V948R	Epidermal growth factor receptor	Homo sapiens

PDB: 8EME — TYR EGFR_HUMAN

Total number of chains: 0

Spatial label	Dihedral label	Number of Chains	Representative

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism