Ligand: A1IEZ

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9FRDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 9FRDA 2.06 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IEZ Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9FQPA 2.495 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IEZ Type1.5_Back 701 - 1020 0 None V948R Epidermal growth factor receptor

Ligand: A1IEZ

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9FRDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 9FRDA 2.06 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IEZ Type1.5_Back 696 - 1019 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9FQPA 2.495 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai A1IEZ Type1.5_Back 701 - 1020 0 None V948R Epidermal growth factor receptor Homo sapiens

Ligand: A1IEZ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism