Ligand: 7XU

Total number of chains: 5
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 5X28A
DFGin BLBtrans 4 5X2FB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 5X28A 2.952 None DFGin‑BLAminus in-in in-none 7XU Type1 697 - 1020 9 None L858R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FA 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 700 - 1014 12 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FB 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 699 - 1010 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FC 2.2 Inactive DFGin‑BLBtrans out-out out-none 7XU Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5X2FD 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 697 - 1014 7 None T790M,V948R Epidermal growth factor receptor

Ligand: 7XU

Total number of chains: 5
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 5X28A
DFGin BLBtrans 4 5X2FB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 5X28A 2.952 None DFGin‑BLAminus in-in in-none 7XU Type1 697 - 1020 9 None L858R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2FA 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 700 - 1014 12 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2FB 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 699 - 1010 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2FC 2.2 Inactive DFGin‑BLBtrans out-out out-none 7XU Type1 700 - 1014 13 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5X2FD 2.2 Inactive DFGin‑BLBtrans out-out out-out 7XU Type1 697 - 1014 7 None T790M,V948R Epidermal growth factor receptor Homo sapiens

Ligand: 7XU

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism