Ligand: 3QS

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4RJ8A
DFGin BLBtrans 1 50.0% 4RJ3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CDK2 CDK2_HUMAN 4RJ3A 1.63 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaioi APEdist_oooo 3QS Type1 1 - 295 0 None None Cyclin-dependent kinase 2
TYR EGFR EGFR_HUMAN 4RJ8A 2.5 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 3QS Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor

Ligand: 3QS

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4RJ8A
DFGin BLBtrans 1 50.0% 4RJ3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CDK2 CDK2_HUMAN 4RJ3A 1.63 Inactive DFGin‑BLBtrans out-na out-out nonTYR APEdihe_aaioi APEdist_oooo 3QS Type1 1 - 295 0 None None Cyclin-dependent kinase 2 Homo sapiens
TYR EGFR EGFR_HUMAN 4RJ8A 2.5 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai 3QS Type1 697 - 1018 0 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens

Ligand: 3QS

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism