Ligand: 5N3

Total number of chains: 1
Spatial label Dihedral label Number of Chains Representative
DFGin BLAplus 1 5EDQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 5EDQA 2.8 Inactive DFGin‑BLAplus in-in none-none 5N3 Type1.5_Back 697 - 1018 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor

Ligand: 5N3

Total number of chains: 1
Spatial label Dihedral label Number of Chains Representative
DFGin BLAplus 1 5EDQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 5EDQA 2.8 Inactive DFGin‑BLAplus in-in none-none 5N3 Type1.5_Back 697 - 1018 16 None T790M,L858R,E865A,E866A,K867A Epidermal growth factor receptor Homo sapiens

Ligand: 5N3

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism