PDB: 6V6O — TYR EGFR_HUMAN

Total number of chains: 8
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 50.0% 6V6OD
DFGin BLBtrans 4 50.0% 6V6OA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 6V6OC 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao QQM Type1 701 - 1011 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OD 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OE 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OH 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai QQM Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OA 2.1 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaai QQM Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OB 2.1 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaao QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OF 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai QQM Type1 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6V6OG 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai QQM Type1 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor

PDB: 6V6O — TYR EGFR_HUMAN

Total number of chains: 8
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 50.0% 6V6OD
DFGin BLBtrans 4 50.0% 6V6OA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 6V6OC 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_nniai APEdist_aaao QQM Type1 701 - 1011 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OD 2.1 Inactive DFGin‑BLBplus out-out out-out TYR APEdihe_oiiai APEdist_aaai QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OE 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OH 2.1 Inactive DFGin‑BLBplus out-out out-none TYR APEdihe_niiai APEdist_aaai QQM Type1 700 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OA 2.1 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaai QQM Type1 701 - 1007 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OB 2.1 Inactive DFGin‑BLBtrans out-out out-out TYR APEdihe_oiiai APEdist_aaao QQM Type1 701 - 1014 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OF 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai QQM Type1 701 - 1012 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 6V6OG 2.1 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai QQM Type1 701 - 1009 0 None T790M,V948R Epidermal growth factor receptor Homo sapiens

PDB: 6V6O — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism