Ligand: FI3

Total number of chains: 2
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 4R5SA
DFGout BBAminus 1 4R6VA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 4R5SA 3.001 Inactive DFGin‑BLAminus in-out in-out FI3 Type1.5_Back 697 - 1018 9 None L858R Epidermal growth factor receptor
TYR FGFR4 FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus in-in none-none FI3 Type1.5_Back 445 - 750 17 None V550L,R664E Fibroblast growth factor receptor 4

Ligand: FI3

Total number of chains: 2
Spatial label Dihedral label Number of Chains Representative
DFGin BLAminus 1 4R5SA
DFGout BBAminus 1 4R6VA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 4R5SA 3.001 Inactive DFGin‑BLAminus in-out in-out FI3 Type1.5_Back 697 - 1018 9 None L858R Epidermal growth factor receptor Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus in-in none-none FI3 Type1.5_Back 445 - 750 17 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens

Ligand: FI3

Total number of chains: 0
Spatial label Dihedral label Number of Chains Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism