Ligand: FI3

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4R5SA
DFGout BBAminus 1 50.0% 4R6VA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 4R5SA 3.001 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_nnoao APEdist_aaai FI3 Type1.5_Back 697 - 1018 0 None L858R Epidermal growth factor receptor
TYR FGFR4 FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan FI3 Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4

Ligand: FI3

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4R5SA
DFGout BBAminus 1 50.0% 4R6VA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 4R5SA 3.001 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_nnoao APEdist_aaai FI3 Type1.5_Back 697 - 1018 0 None L858R Epidermal growth factor receptor Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan FI3 Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens

Ligand: FI3

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism