9DF4

EGFR (Epidermal growth factor receptor)
Group: TYR
Uniprot: EGFR_HUMAN
Organism: Homo sapiens
Domain boundary: 712 - 970
Resolu: 1.78

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in A1A4E Type1.5_Back 701 - 1019 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       702        712        722        732 
ggsgeapnQA LLRILKETEF KKIKVLGSGA FGTVYKGLWI 
       742        752        762        769 
PEGEKVKIPV AIKELReats pkANKEILDE AYVMASVDSV 
       779        789        799        809 
DNPHVCRLLG ICLTSTVQLI TQLMPFGCLL DYVREHKDNI 
       819        829        839        849 
GSQYLLNWCV QIAKGMNYLE DRRLVHRDLA ARNVLVKTPQ 
       859        869        879        889 
HVKITDFGLA KLLGAEEKEY HAEGGKVPIK WMALESILHR 
       899        909        919        929 
IYTHQSDVWS YGVTVWELMT FGSKPYDGIP ASEISSILEK 
       939        949        959        969 
GERLPQPPIC TIDVYMIMRK CWMIDADSRP KFRELIIEFS 
       979        989        999       1009 
KMARDPQRYL VIQGDERMHL PSPTDSNFYR ALMDEEDmdd 
      1019 
vvdadEYLIP qqg
Lower-case residues are disordered in structure.
Mutations: V948R
Phosphorylation: None