Protein kinases in complex with 1C9 (Dacomitinib)

Total number of genes: 1
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 4I23A
DFGin BLBtrans 2 4I24B
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4I23A 2.8 Active DFGin BLAminus in-in in-in 1C9 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4I24A 1.8 Inactive DFGin BLBtrans out-out out-out 1C9 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4I24B 1.8 Inactive DFGin BLBtrans out-out out-in 1C9 Type1

Protein kinases in complex with 1C9

Total number of genes: 1
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 1 4I23A
DFGin BLBtrans 2 4I24B
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4I23A 2.8 Active DFGin BLAminus in-in in-in 1C9 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4I24A 1.8 Inactive DFGin BLBtrans out-out out-out 1C9 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4I24B 1.8 Inactive DFGin BLBtrans out-out out-in 1C9 Type1

Protein kinases in complex with 1C9

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type