Ligand: A1IZ8

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 2 100.0% 9GC5A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 9GC5A 1.909 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GC5B 1.909 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor

Ligand: A1IZ8

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBtrans 2 100.0% 9GC5A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 9GC5A 1.909 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 9GC5B 1.909 Inactive DFGin‑BLBtrans out-out out-none TYR APEdihe_nniai APEdist_aaai A1IZ8 Type1.5_Back 699 - 1012 0 None V948R Epidermal growth factor receptor Homo sapiens

Ligand: A1IZ8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism