Ligand: 0WN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4G5PA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR EGFR EGFR_HUMAN 4G5PA 3.17 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0WN Type1 696 - 1016 0 None T790M Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4G5JA 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0WN, 0WM, 0WM Type1, Allosteric, Allosteric 696 - 1016 0 None None Epidermal growth factor receptor

Ligand: 0WN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4G5PA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR EGFR EGFR_HUMAN 4G5PA 3.17 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0WN Type1 696 - 1016 0 None T790M Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4G5JA 2.8 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 0WN, 0WM, 0WM Type1, Allosteric, Allosteric 696 - 1016 0 None None Epidermal growth factor receptor Homo sapiens

Ligand: 0WN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism